apelike Posted February 15, 2021 Share Posted February 15, 2021 6 hours ago, El Cid said: The vaccines have a range of effectivness, from around 60% - 95% Would it be better to just go with the one that gives 95% effectivness? The problem with that (as I see it) is that if every government went with that idea there would many less people vaccinated in a timely manner because of the demand for just one vaccine leading to shortages. I would have though that vaccinating as many people as possible in the shortest time with whatever is available at present would be the best way to go. If there are shortages of one, as already seen in the EU and US then others can be used. Don't forget, the whole word wants vaccines and is the reason why many are available now and why so many are in trials, over 300 so far. No one has mentioned cost but the Oxford/AstraZeneca one is £1.78 per shot whereas the Pfizer/BioNTec is £10.53 so that may also be a factor. Link to comment Share on other sites More sharing options...
El Cid Posted February 15, 2021 Share Posted February 15, 2021 The Oxford trial found with two doses its vaccine was 62% effective. The Oxford-AstraZeneca vaccine is much cheaper, although neither the UK nor the US can match the EU’s $2.15 deal: they are expecting to pay about $3 and $4, respectively, per dose. South Africa’s government found itself on the defensive this week after a senior health official revealed that 1.5 million doses of the Oxford and AstraZeneca vaccine just purchased for use among health workers would cost $5.25 (£3.84; €4.32) a dose, more than twice what the European Union is paying at $2.15. The Oxford/AstraZeneca vaccine is much cheaper, with the company saying it will cost the government "the same as a cup of coffee". Sky News understands it will cost a little under £3 per dose, with two doses needed. https://www.bmj.com/content/372/bmj.n281 Final data from the Pfizer vaccine found it offers 95% protection against the virus after two doses. Pfizer, at $20 (£15) If you read a news article, then another, each article gives a different effectivness and price. https://news.sky.com/story/covid-19-vaccines-how-do-the-moderna-and-pfizer-coronavirus-jab-candidates-compare-12134062 Link to comment Share on other sites More sharing options...
Thirsty Relic Posted February 15, 2021 Share Posted February 15, 2021 Listening to the Government's info slot tonight from 5pm on BBC, they really confused me. Previously, they had said that you got your immunity from 2 doses of the vaccine and that they protected you from the virus and its variants. Tonight one of them said we'd also need a vaccine "top-up" in the Autumn to beat these variants, and that we may need an annual Covid jab on top of that. So, if we sign up to the vaccine, it means 3 jabs this year, and annual top-ups from then on? Link to comment Share on other sites More sharing options...
enntee Posted February 15, 2021 Share Posted February 15, 2021 What do you think that the difference is (for the patient) between sanitised hands and rubber gloves? Link to comment Share on other sites More sharing options...
enntee Posted February 15, 2021 Share Posted February 15, 2021 14 minutes ago, Thirsty Relic said: Listening to the Government's info slot tonight from 5pm on BBC, they really confused me. Previously, they had said that you got your immunity from 2 doses of the vaccine and that they protected you from the virus and its variants. Tonight one of them said we'd also need a vaccine "top-up" in the Autumn to beat these variants, and that we may need an annual Covid jab on top of that. So, if we sign up to the vaccine, it means 3 jabs this year, and annual top-ups from then on? The critical word is "may". There is no need to be confused. Knowledge is increasing, the longer the pandemic continues. If the current vaccines prove effective against variants, then boosters become less likely. If they are not effective against variants, boosters will be needed. Why would you not "sign up" to being vaccinated? Link to comment Share on other sites More sharing options...
El Cid Posted February 15, 2021 Share Posted February 15, 2021 17 minutes ago, Thirsty Relic said: Listening to the Government's info slot tonight from 5pm on BBC, they really confused me. Previously, they had said that you got your immunity from 2 doses of the vaccine and that they protected you from the virus and its variants. Tonight one of them said we'd also need a vaccine "top-up" in the Autumn to beat these variants, and that we may need an annual Covid jab on top of that. So, if we sign up to the vaccine, it means 3 jabs this year, and annual top-ups from then on? If you have the flu vaccine and its the right varriant, its around 50% effective. If its a different variant, the vaccines effectivness is very poor, maybe around 20% Link to comment Share on other sites More sharing options...
apelike Posted February 16, 2021 Share Posted February 16, 2021 3 hours ago, El Cid said: The Oxford trial found with two doses its vaccine was 62% effective. The Oxford-AstraZeneca vaccine is much cheaper, although neither the UK nor the US can match the EU’s $2.15 deal: they are expecting to pay about $3 and $4, respectively, per dose. South Africa’s government found itself on the defensive this week after a senior health official revealed that 1.5 million doses of the Oxford and AstraZeneca vaccine just purchased for use among health workers would cost $5.25 (£3.84; €4.32) a dose, more than twice what the European Union is paying at $2.15. The Oxford/AstraZeneca vaccine is much cheaper, with the company saying it will cost the government "the same as a cup of coffee". Sky News understands it will cost a little under £3 per dose, with two doses needed. https://www.bmj.com/content/372/bmj.n281 Final data from the Pfizer vaccine found it offers 95% protection against the virus after two doses. Pfizer, at $20 (£15) If you read a news article, then another, each article gives a different effectivness and price. https://news.sky.com/story/covid-19-vaccines-how-do-the-moderna-and-pfizer-coronavirus-jab-candidates-compare-12134062 You seem to be missing the point made as to why its better to go for a mix and not just one vaccine alone that may be 95% effective! The first link also states that the UK has basically spent money on "securing 267 million doses of five different types, according to the National Audit Office.2." Link to comment Share on other sites More sharing options...
petemcewan Posted February 16, 2021 Share Posted February 16, 2021 (edited) El Cid, "Which one would that be". Based on this and my own reading. My choice would be mRNA. That's the one I got. But you don't get a choice. Side effects caused by either one of the vaccine being dished out; appear to me to be innocuous-accept for sever allergic reaction. A major consideration for me,when studying which vaccine would I like to get, has been the T/B cell activation by the vaccines. https://www.ouh.nhs.uk/working-for-us/staff/covid-staff-faqs-vaccine.aspx https://www.nature.com/articles/s41591-020-01194-5 https://www.nature.com/articles/s41586-020-2814-7 Edited February 16, 2021 by petemcewan Link to comment Share on other sites More sharing options...
Annie Bynnol Posted February 16, 2021 Share Posted February 16, 2021 3 hours ago, petemcewan said: El Cid, "Which one would that be". Based on this and my own reading. My choice would be mRNA. That's the one I got. But you don't get a choice. Side effects caused by either one of the vaccine being dished out; appear to me to be innocuous-accept for sever allergic reaction. A major consideration for me,when studying which vaccine would I like to get, has been the T/B cell activation by the vaccines. https://www.ouh.nhs.uk/working-for-us/staff/covid-staff-faqs-vaccine.aspx https://www.nature.com/articles/s41591-020-01194-5 https://www.nature.com/articles/s41586-020-2814-7 B-lymphocytes and T-lymphocytes are the basics of how the body protects itself from viruses and how vaccinations work and any study or trial would be based around their appearance, stimulation by vaccine and production in the body, effectiveness and longevity. Not sure why you have selected theses two Springer Nature articles from the dozens of available articles on the progress of early vaccination trials from this and other publications. Is there something significantly novel about these two trials? The estimated study date for completion of the trials are March and August so any approval for use in the form of vaccines is months away. Springer publications like Nature and Nature Medicine are not aimed at users like us, nor are they aimed at health professionals they are for researchers to publish their progress/findings. Link to comment Share on other sites More sharing options...
Hans-solo Posted February 16, 2021 Share Posted February 16, 2021 Had my covid jab 4th of Feb its the Oxford one big mistake feel so rough headaches cough high temp skin rashes muscle cramps just getting through worse now thank god anyone else had reactions speaking to doctor today see if its worth getting second jab put me right off I know getting covid itself could be worse just felt so bad with jab Link to comment Share on other sites More sharing options...
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